Author Question: Medically Induced Coma

Terry asks:

The information you sent me last time has been great for my story! One thing I forgot to ask though, and it is very important to the ending is this: When my character finally comes out of his coma I need to know two things:

1. He was put into a drug induced coma because of a head injury suffered in an automobile crash. Is it possible he can come out of that coma on his own? Like just open his eyes after about two weeks?

2.  When they finally take the breathing tube out of him how long will it take before he will be able to speak? I want him to be able to tell about what he went through in the coma from his perspective as soon as he can.

I thank you in advance for any and all info you can give me. I really appreciate your help. Your site is THE BEST for writers!!

Jordyn Says:

Hi, Terry!

Thanks for sending me your question.

In your first question it’s hard for me to tell if you mean is it possible for this patient to just wake up from a drug induced coma— like the drugs are still infusing? If that’s the case, then no. The medications would have to be stopped before the patient would have a chance of waking up. In fact, the type of medication on board often plays into whether or not a patient can be declared brain dead.

If a patient still has narcotic and/or sedative medications in their system they cannot be declared brain dead. So first, the medication(s) given has to wear off. Most often, these medications are given as continuous infusions and are weaned down slowly and not abruptly discontinued. If after that has happened then yes— a patient may just open his eyes.

More often, patients are slow to come about. The first time they open their eyes, it might only be for a brief period of time. They may have muscle movements first. Generally, the medical team knows they’re improving when they can respond purposefully to pain by first pulling away from the stimulus, then by trying to push the stimulus away, and then by opening their eyes and understanding and following commands. It’s usually a slow process– from days to weeks (and even months to years) depending on the type of head injury the person suffered.

In regards to your second question, how long before he can speak? If he is awake and able to speak then he should be able to speak right away if the brain injury did not affect the speech sensitive areas. Some patients are extubated (or taken off breathing machines) and they’re not fully alert and responding to commands, but may be breathing adequately enough that they no longer need a ventilator. Many of these patients do have a trach in place, though.

That being said, if your character is awake and alert, his voice will sound soft, hoarse, and strained. His throat will hurt. He may have some trouble swallowing. His voice won’t have the same strength right after the breathing tube comes out as it did before. It will take some time to return to normal. The shorter the intubation the more quickly the patient’s voice should return to normal.  However, he should be able to share his story.

Good luck!

Traumatic Brain Injuries: A Primer

The brain is our most complex organ and perhaps the most difficult to help heal. The biggest challenge is its protective covering: the skull. Management of acute traumatic brain injury, or TBI, typically involves manipulating the three components within the skull: the brain, the blood, and the cerebrospinal fluid (CSF).

What is the purpose of each of these components? The brain is the body’s supercomputer. The blood delivers oxygen and nutrients to feed the cells or neurons. The CSF nourishes the brain, helps remove waste products, and keeps the brain buoyant.

What happens when something is significantly injured? It swells. Think about a time you saw someone with a really bad sprained ankle. What happened? It blew up like a balloon. The same thing happens to the brain with a traumatic injury. It swells.

Unlike an ankle, brain swelling is inhibited by the skull but the pressure inside the head can continue to rise if swelling is unchecked. Too much pressure inside the skull (it can’t move) and blood flow diminishes, thereby starving cells of oxygen, which then swell more.

We can measure the pressure inside your skull, or intracranial pressure (ICP), by placing a sensor into a ventricle (a ventriculostomy).  A normal ICP is 7-15mmHg. Cerebral edema can be insidious as swelling peaks 48-72 hours post injury. A patient can initially present following commands. Then in 2-3 days, develop cerebral edema to the point of herniation (which means brain contents shifting) and die.

What happens when a patient develops significant cerebral edema and ICP pressures skyrocket?

First bad thing: Blood flow is reduced. The brain is very sensitive to blood flow and greedy for oxygen. If there is diminished blood flow, neurons (brain cells) begin to die. If there is no blood flow, the brain will die. You may have heard the term brain death. This is determined by several factors but the definitive one is by taking the patient to radiology and doing a brain flow study. Roughly, a dye is injected into the blood and x-rays are taken. If there is no blood flow, the patient is declared brain dead.

Second bad thing: Brain contents shift into areas where they’re not supposed to be. This is called herniation. When neurons are compressed, they don’t function properly and will begin to die as well. When brain cells die, machines and medications have to take over their function to keep the patient alive.

Unfortunately, if brain death has occurred, the medical team will start discussing withdrawal of care with the family.

***Content reposted from January, 12, 2011.***

Author Question: Car versus Pedestrian

Alex Asks:

My character suffers the following injuries. I want the injuries to be severe enough that they require immediate surgery, but also that he recovers after about a month in the hospital and a stay in rehab.

carpedistrian1. Character is standing in the road, tries to run but is hit by the car front on.  Body smashes into the windscreen, sending him up into the air.

2. Hits his head on the pavement on landing and suffers broken bones as a result.

3. He blacks out from the impact and wakes up several hours later. In this instance, would he be able to survive for several hours with the kinds of injuries he could have?

4. Possible injuries I thought he could have included: bleeding on the brain, broken leg/s and/or arms, fractured ribs which could cause a puncture to one of his lungs.

5. As a result he suffers from retrograde amnesia when he wakes up at the scene because of the injuries to his brain. Cannot remember his name/where he is or other events in his memory. Again here I am not sure what kind of specific head trauma could cause this.

6. After surgery to the brain, he is put into an induced coma to monitor the swelling. He will eventually wake up from this about a month later.

Jordyn Says:

The accident you describe would include some very serious injuries— perhaps not even survivable. It’s not just the injuries the character suffers getting thrown from the impact onto the pavement, but also the injuries he suffers from getting hit by the car. An impact that is so violent that it throws someone into the air would also likely shatter the windshield indicating to EMS responders that there was a lot of violent energy associated with this collision— which means bad things for the patient.

My first opinion is if you want this character to wake up in a few hours would be that he doesn’t fall directly on his head after he’s thrown into the air from the first impact. Overall, for your scenario, you might want to lessen the violence of this crash if you want him up in a few hours. It wouldn’t be surprising for this patient to require surgery to fix broken bones and/or internal bleeding.

A pedestrian surviving this crash is not impossible but it is more on the improbable side. This patient will have a lengthy hospital stay. May not wake up for days or months— not just hours. What you outline is a high speed impact to a pedestrian.

To answer some of your medical questions— surgery may be required for the bleeding on the brain depending on its location. All patients who have a brain bleed do not necessarily go to surgery. A punctured lung will require a chest tube to be placed which further complicates your patient’s medical picture. This patient would be placed on a breathing machine for sure to stabilize him until all these injuries could be sorted out.

Could a patient with a significant brain bleed be conscious at the scene after the accident? Yes. There is a specific type of brain bleed that fits this scenario called an epidural bleed. It does have a characteristic lucid period before the patient becomes unconscious again. It does require surgery to correct. If no surgical intervention is done then the patient will likely die. Honestly, as a writer, you have a lot of leeway in regards to what to do with amnesia. Any type of traumatic brain injury (and this certainly qualifies) could cause amnesia.

Medically induced comas are used frequently in medicine as a way to help control brain swelling. However, the medicines are not used forever. Peak brain swelling usually occurs 48-72 hours after the injury. After this time has passed, the medical team will evaluate when to decrease the medications keeping the patient in the coma. Keep in mind, even after these medications are discontinued, the patient may never wake up. Further studies would need to be done to determine the extent of the damage to his brain. These changes will evolve over time becoming more stable the more time that goes on.

My recommendation would be to lessen the severity of the crash. The car hits him, he hit the windshield, breaks it and then falls to the ground. This alone could cause a femur fracture and brain injury for which he could suffer amnesia and require surgery. If it’s an epidural bleed then he gets surgery, perhaps with some swelling and therefore the medically induced coma, but wakes up in a month. The leg is set in surgery with pinning or a rod. I think just having these two things is enough for your scenario.

All the rest might prove too complicating.